SCHEMBL8675472

SCHEMBL8675472

O=S(=O)(O)c1c(/N=N/c2c(O)ccc3ccccc23)c(O)cc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 9/20 0.73
CTRC Q99895 2/20 0.73
MAPT P10636 5/20 0.61
KMT2A Q03164 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
MAPK1 P28482 3/20 0.61
GAA P10253 2/20 0.61
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
TSHR P16473 1/20 0.60
PTPRA P18433 1/20 0.60
PTPRB P23467 1/20 0.60
CYP2C19 P33261 1/20 0.60
HIF1A Q16665 1/20 0.60
RAPGEF4 Q8WZA2 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MEN1 O00255 3/20 0.54
GLO1 Q04760 2/20 0.54
THRB P10828 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7581239 0.86 CYP1A2 (0.63) MPLCTRCMAPTKMT2ATDP1
SCHEMBL8675478 0.85 MPL (0.64) MPLCTRCMAPTKMT2ATDP1
SCHEMBL7247118 0.84 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL8947347 0.84 MPL (0.63) MPLCTRCMAPTKMT2ATDP1
SCHEMBL3010602 0.84 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL29393603 0.84 MPL (0.63) MPLCTRCMAPTKMT2ATDP1
SCHEMBL30371538 0.84 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL344640 0.84 MPL (0.63) MPLCTRCMAPTKMT2ATDP1
SCHEMBL29362358 0.84 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL9577835 0.83 MPL (0.61) MPLCTRCMAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10337199-A None JP disclosed
JP-H10337199-A NUCLEIC ACID STAIN, DETECTION OF DOUBLE-STRANDED NUCLEIC ACID USING THE SAME AND DETECTION REAGENT FOR TARGETED NUCLEIC ACID UNITIKA LTD 1998-12-22 JP disclosed