SCHEMBL344640

SCHEMBL344640

O=S(=O)(O)c1c(N=Nc2c(O)ccc3ccccc23)ccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 5/20 0.63
CTRC Q99895 2/20 0.63
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
TSHR P16473 1/20 0.62
PTPRA P18433 1/20 0.62
PTPRB P23467 1/20 0.62
CYP2C19 P33261 1/20 0.62
HIF1A Q16665 1/20 0.62
RAPGEF4 Q8WZA2 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MAPT P10636 7/20 0.59
MAPK1 P28482 4/20 0.59
KMT2A Q03164 4/20 0.59
TDP1 Q9NUW8 4/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 4/20 0.57
KDM4E B2RXH2 2/20 0.57
NPC1 O15118 2/20 0.57
THRB P10828 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393603 1.00 MPL (0.63) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL8947347 1.00 MPL (0.63) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL29912833 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577832 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577835 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577808 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577763 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL14549104 0.90 CYP1A2 (0.79) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL10884144 0.89 CYP1A2 (0.60) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL29617555 0.87 MPL (0.53) MPLCTRCCYP1A2CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances CLARIANT INTERNATIONAL LTD. (CH) 2021-09-07 US disclosed
CN-108273478-B Formaldehyde removal composition and product 李怀玉 2021-03-02 CN disclosed
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group CLARIANT INTERNATIONAL LTD. (CH) 2019-09-10 US disclosed
EP-2553026-B1 METAL OXIDE PARTICLES AFTER-TREATED WITH ORGANIC PHOSPHORUS COMPOUNDS MERCK PATENT GMBH (DE) 2018-03-28 EP disclosed
US-9834635-B2 Polymers based on arcrylic, methacrylic or ethacrylic amidoalkyl sulfonic acid or salts and carboxyalky acrylate, methacrylate or ethacrylate or oligomers of said carboxy compounds CLARIANT INTERNATIONAL LTD. (CH) 2017-12-05 US disclosed
EP-2552385-B1 PREPARATIONS COMPRISING DIHYDROXYACETONE MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
US-20170105910-A1 UV FILTER CAPSULE BASF SE (DE) 2017-04-20 US disclosed
US-9592185-B2 Compositions containing hydrogen peroxide or substances releasing hydrogen peroxide CLARIANT INTERNATIONAL LTD. (CH) 2017-03-14 US disclosed
US-9526687-B2 Polymers based on sulfonic acids, amides and special cross-linking agents CLARIANT INTERNATIONAL LTD. (CH) 2016-12-27 US disclosed
EP-2420222-B1 Nail varnish with velvet feel ECKART GMBH (DE) 2016-12-14 EP disclosed
US-20020182234-A1 Self-foaming or foam-like preparations BEIERSDORF AKTIENGESELLSCHAFT 2002-12-05 US disclosed
US-20020176832-A1 O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers CLARIANT INTERNATIONAL LTD. (CH) 2002-11-28 US disclosed
US-20020155076-A1 Gel creams in the form of O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers CLARIANT INTERNATIONAL LTD. (CH) 2002-10-24 US disclosed
US-20020102289-A1 Cosmetic or dermatological impregnated wipes BEIERSDORF AG (DE) 2002-08-01 US disclosed
EP-0649406-B1 CARBAZOLE DERIVATIVES AND THEIR USE IN COSMETICS, ESPECIALLY FOR MAKE-UP OREAL (FR) 1998-12-23 EP disclosed
EP-0038208-A1 Dispersion polymerisation process for making toner XEROX CORPORATION (US) 1981-10-21 EP disclosed
US-4135925-A BY PRESSURE ON PIGMENTS IN POLYMERIC MATRIX XEROX CORPORATION (US) 1979-01-23 US disclosed
US-4113482-A TWO DIFFERENTLY COLORED PIGMENT PARTICLES IN POLYMERIC MATRIX XEROX CORPORATION (US) 1978-09-12 US disclosed
US-4077804-A Method of producing toner particles by in-situ polymerization and imaging process XEROX CORPORATION (US) 1978-03-07 US disclosed
US-4063530-A Image fixing XEROX CORPORATION (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020182234-A1 Self-foaming or foam-like preparations FFAR2, LIPA, FFAR1 MPL 4411/4885CTRC 3411/4885CYP1A2 1133/4885
US-20020102289-A1 Cosmetic or dermatological impregnated wipes CUTA, PWWP2B, WIZ MPL 2537/4885CTRC 3326/4885CYP1A2 3858/4885
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances GPX4, LPO, CAT MPL 2837/4885CTRC 872/4885CYP1A2 812/4885
US-20170105910-A1 UV FILTER CAPSULE UROD, MITF, NISCH MPL 2774/4885CTRC 1453/4885CYP1A2 201/4885
US-20020176832-A1 O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers AGPAT2, PHOSPHO1, MBOAT1 MPL 3251/4885CTRC 4660/4885CYP1A2 2784/4885
US-20020155076-A1 Gel creams in the form of O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers AGPAT2, ACMSD, POLR1C MPL 3951/4885CTRC 4504/4885CYP1A2 2460/4885
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group ADH5, ADH1A, ADH1C MPL 4266/4885CTRC 785/4885CYP1A2 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.