Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.53 |
| ▸ | FABP3 | P05413 | 2/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162818 | 0.87 | FABP4 (0.67) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL21550418 | 0.83 | FABP4 (0.45) | FABP4FABP3FABP5ALDH1A1CA1 | |
| SCHEMBL7608 | 0.81 | CA1 (0.52) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL15761600 | 0.77 | FABP3 (0.50) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL18119971 | 0.75 | FABP4 (0.79) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL21297046 | 0.75 | FABP4 (0.51) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL10952493 | 0.74 | FABP4 (0.64) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL8989764 | 0.73 | FABP4 (0.69) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL13278332 | 0.72 | GABRA1 (0.48) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL8243105 | 0.71 | FABP4 (0.67) | FABP4FABP3FABP5ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |