SCHEMBL7608

SCHEMBL7608

Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
RAPGEF4 Q8WZA2 6/20 0.50
F2 P00734 3/20 0.47
PRSS1 P07477 3/20 0.47
PRSS2 P07478 3/20 0.47
PRSS3 P35030 3/20 0.47
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 3/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 1/20 0.41
GFER P55789 1/20 0.41
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
NR3C2 P08235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4013923 0.85 RAPGEF4 (0.63) CA1CA2MMP1MMP2MMP9
SCHEMBL23172333 0.84 CA1 (0.44) CA1CA2MMP1MMP2MMP9
Pyridine SCHEMBL4753241 0.84 ALDH1A1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL3609619 0.82 GAA (0.40) CA1CA2MMP1MMP2MMP9
SCHEMBL11139384 0.82 RAPGEF4 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL21872115 0.81 RAPGEF4 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL8675650 0.81 FABP4 (0.53) CA1CA2MMP1MMP2MMP9
SCHEMBL640928 0.80 PTGS1 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL3440241 0.80 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL9521335 0.80 L3MBTL1 (0.42) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2958 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP claimed
CN-119751501-A Symmetrical phosphinic acid compound, symmetrical phosphinic acid amino acid derivative, and preparation methods and application thereof 西交利物浦大学 2025-04-04 CN claimed
US-12258343-B2 Method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-[1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine BAYER AKTIENGESELLSCHAFT (DE) 2025-03-25 US claimed
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
EP-3901161-B1 CYCLIC DINUCLEOTIDE PRODRUG MOLECULE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHENZHEN YING BIOPHARMACEUTICAL CO LTD (CN) 2025-01-22 EP claimed
CN-111423483-B Cyclic dinucleotide prodrug molecule as well as preparation method and application thereof 英诺生物制药(深圳)有限公司 2025-01-17 CN claimed
EP-3247703-B1 IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) 2024-10-16 EP claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-118356816-A Acid-resistant composite nanofiltration membrane based on polytetrafluoroethylene base membrane improvement and preparation method and application thereof 浙江理工大学 2024-07-19 CN claimed
EP-0576228-A1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-12-29 EP claimed
US-5252756-A Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-10-12 US claimed
EP-0061761-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-05-18 EP claimed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed
EP-0101985-B1 OLIGONUCLEOTIDE DERIVATIVES AND PRODUCTION THEREOF WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1987-09-23 EP claimed
US-4529796-A Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity BAKER INSTRUMENTS CORPORATION (US) 1985-07-16 US claimed
EP-0101985-A1 Oligonucleotide derivatives and production thereof WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1984-03-07 EP claimed
EP-0061760-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed
US-4326076-A Method for preparing the optically active isomer of 2,2-[[5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-2,3-naphthalene-diyl]bis(oxy)]bis[N,N-dipropylacetamide] E. R. SQUIBB & SONS, INC. (US) 1982-04-20 US claimed
US-4159998-A Process for the preparation of 2-(7-hydroxyalkyl)-4R, 4S or 4RS -hydroxy-cyclopent-2-enone MILES LABORATORIES, INC. (US) 1979-07-03 US claimed