SCHEMBL8675724

SCHEMBL8675724

Cc1ccccc1S(=O)(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
PKM P14618 1/20 0.41
MAPT P10636 3/20 0.41
RAB9A P51151 1/20 0.41
POLB P06746 1/20 0.41
HRH2 P25021 1/20 0.41
HRH1 P35367 1/20 0.41
PTPN1 P18031 1/20 0.40
PARP10 Q53GL7 1/20 0.40
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
PPARA Q07869 1/20 0.39
MAOB P27338 1/20 0.39
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2386879 0.81 CA12 (0.49) L3MBTL1MAPTPOLBHRH2HRH1
SCHEMBL6907032 0.81 CYP1A2 (0.45) TDP1PKMMAPTRAB9APOLB
SCHEMBL2468529 0.80 MAPT (0.45) L3MBTL1PKMMAPTRAB9APARP10
SCHEMBL19998344 0.80 PKM (0.64) L3MBTL1PKMMAPTRAB9APOLB
SCHEMBL8654494 0.77 KMT2A (0.45) L3MBTL1TDP1PKMPOLBCYP2C9
SCHEMBL39561 0.76 PPARA (0.63) L3MBTL1PKMMAPTRAB9APARP10
SCHEMBL28619068 0.76 KMT2A (0.56) L3MBTL1PKMRAB9APOLBKMT2A
SCHEMBL23616751 0.75 NPC1 (0.41) L3MBTL1MAPTPOLBHRH2HRH1
SCHEMBL15828758 0.74 MAPT (0.54) L3MBTL1TDP1PKMMAPTRAB9A
SCHEMBL15633667 0.73 GAA (0.67) L3MBTL1PKMMAPTRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5837746-A Coreactive photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US disclosed
US-5532112-A PHOTOPOLYMERIZATION CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP disclosed