SCHEMBL2468529

SCHEMBL2468529

CC(C)(O)C(=O)c1ccc(OCCOS(C)(=O)=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 2/20 0.41
PKM P14618 1/20 0.41
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PPARA Q07869 1/20 0.39
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12994159 0.82 KMT2A (0.41) MAPTALDH1A1
SCHEMBL15828758 0.81 MAPT (0.54) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL19998344 0.81 PKM (0.64) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL2386879 0.81 CA12 (0.49) MAPTL3MBTL1ALDH1A1PPARANPC1
SCHEMBL8675724 0.80 L3MBTL1 (0.44) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL24161906 0.80 MAPT (0.49) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL9946190 0.80 MAPT (0.49) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL36443 0.80 GAA (0.56) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL10713224 0.80 TP53 (0.58) L3MBTL1GAARAB9AALDH1A1TP53
SCHEMBL402554 0.80 L3MBTL1 (0.58) MAPTL3MBTL1GAAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3668906-B1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST AS (DK) 2023-06-07 EP disclosed
CN-111133009-B Amide and imide photoinitiators 科洛普拉斯特公司 2022-10-04 CN disclosed
US-11034779-B2 Amide and imide photoinitiators COLOPLAST A/S (DK) 2021-06-15 US disclosed
US-11034779-B2 Amide and imide photoinitiators COLOPLAST A/S (DK) 2021-06-15 US disclosed
US-20200231715-A1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST A/S (DK) 2020-07-23 US disclosed
US-20200231715-A1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST A/S (DK) 2020-07-23 US disclosed
EP-3668906-A1 AMIDE AND IMIDE PHOTOINITIATORS Coloplast A/S (DK) 2020-06-24 EP disclosed
CN-111133009-A Amide and imide photoinitiators 科洛普拉斯特公司 2020-05-08 CN disclosed
WO-2019034221-A1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST A/S (DK) 2019-02-21 WO disclosed
US-8637585-B2 Silsesquioxane photoinitiators BASF SE (DE) 2014-01-28 US disclosed
EP-2370449-A1 SILSESQUIOXANE PHOTOINITIATORS BASF SE (DE) 2011-10-05 EP disclosed
WO-2010063612-A1 SILSESQUIOXANE PHOTOINITIATORS BASF SE (DE) 2010-06-10 WO disclosed
EP-1451615-B1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES NOVARTIS AG (CH) 2007-11-14 EP disclosed
US-6878399-B2 Method for modifying the surface of biomedical articles NOVARTIS AG (CH) 2005-04-12 US disclosed
EP-1451615-A1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES Novartis AG (CH) 2004-09-01 EP disclosed
US-20030219533-A1 Method for modifying the surface of biomedical articles NOVARTIS AG (CH) 2003-11-27 US disclosed
WO-2003042724-A1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES NOVARTIS AG (CH) 2003-05-22 WO disclosed
US-6011077-A DERIVATIVE OF A POLYVINYL ALCOHOL COMPRISING UNITS CONTAINING CROSSLINKABLE OLEFINICALLY UNSATURATED GROUPS, AND UNITS CONTAINING A BONDED PHOTOINITATOR NOVARTIS AG (CH) 2000-01-04 US disclosed
EP-0807269-B1 CROSSLINKABLE POLYMERS CONTAINING PHOTOINITIATORS NOVARTIS AG (CH) 1999-10-20 EP disclosed
EP-0354458-A2 Photoinitiators with a combined structure MERCK PATENT GmbH (DE) 1990-02-14 EP disclosed