Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126076 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL342904 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3130561 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL33584 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3128140 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL1369560 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL2316246 | 0.98 | LMNA (0.46) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| Ammonia Solution, Strong SCHEMBL16720911 | 0.96 | LMNA (0.44) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| Acetic Acid SCHEMBL680584 | 0.92 | PDE4A (0.44) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL616881 | 0.92 | LMNA (0.42) | TDP1LMNAL3MBTL1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798343-A | TREATING GRAM-NEGATIVE BACTERIA WITH HYDROFLUORIC ACID, HYDROLYZING OR METHOLYZING, PERMETHYLATING | FORSCHUNGSINSTITUT BORSTEL INSTITUT FUR EXPERIMENTELLE BIOLOGIE UND MEDIZIN (DE) | 1998-08-25 | — | — | US | disclosed |