Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128140 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL2316246 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL3130561 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1369560 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL33584 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL342904 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL4126076 | 0.94 | LMNA (0.46) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL8675811 | 0.92 | TDP1 (0.48) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL16720911 | 0.92 | LMNA (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL616881 | 0.88 | LMNA (0.42) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486367-B2 | Absorbent article with lotion comprising a polypropylene glycol material | THE PROCTER & GAMBLE COMPANY (US) | 2016-11-08 | — | — | US | claimed |
| EP-2242519-A2 | ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL | The Procter & Gamble Company (US) | 2010-10-27 | — | — | EP | claimed |
| US-20090221978-A1 | ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL | PROCTER & GAMBLE COMPANY, THE | 2009-09-03 | — | — | US | claimed |
| WO-2009102837-A2 | ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2009-08-20 | — | — | WO | claimed |
| US-6616922-B2 | For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user | THE DIAL CORPORATION | 2003-09-09 | — | — | US | claimed |
| US-20030022941-A1 | For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user | Henkel IP & Holding GmbH (DE) | 2003-01-30 | — | — | US | claimed |
| WO-2002076207-A1 | ANTIBACTERIAL COMPOSITIONS | THE DIAL CORPORATION (US) | 2002-10-03 | — | — | WO | claimed |
| CN-118076327-A | Topsheet system for absorbent article | 宝洁公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20230277392-A1 | UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE | THE PROCTER & GAMBLE COMPANY | 2023-09-07 | — | — | US | disclosed |
| WO-2023168374-A1 | UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE | THE PROCTER & GAMBLE COMPANY (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230265268-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | POLYMAX THERMOPLASTIC ELASTOMERS, LLC | 2023-08-24 | — | — | US | disclosed |
| US-20230121636-A1 | UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE | THE PROCTER & GAMBLE COMPANY | 2023-04-20 | — | — | US | disclosed |
| CN-106488758-B | Absorbent article | 尤妮佳股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| US-6386778-B1 | Systems and methods for dispensing multi-component products | THE GILLETTE COMPANY | 2002-05-14 | — | — | US | disclosed |
| US-20020055562-A1 | Gel compositions | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2002-05-09 | — | — | US | disclosed |
| EP-1203141-A1 | LINKAGE OF AGENTS TO TISSUE | Pericor Science, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1202706-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | Pericor Science, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2002007707-A2 | LINKAGE OF AGENTS USING MICROPARTICLES | PERICOR SCIENCE, INC. (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001007009-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001006829-A2 | LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022941-A1 | For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user | CUTA, CHIT1, CLSPN | PDE4A 3145/4885LMNA 1965/4885USP2 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.