SCHEMBL8675874

SCHEMBL8675874

NC(=O)c1ccc(C(=O)NS(=O)(=O)O)c2c3ccc(cc3)c12

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.33
FLT1 P17948 3/20 0.32
FLT4 P35916 3/20 0.32
KDR P35968 3/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
NNMT P40261 1/20 0.30
ERN1 O75460 1/20 0.30
EGFR P00533 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437799 0.79 ALDH1A1 (0.42) NNMTERN1
SCHEMBL44930 0.79 ALDH1A1 (0.42) NNMTERN1
SCHEMBL11799893 0.77 NEU3 (0.44) NNMT
SCHEMBL1538065 0.67 GAA (0.43) CA1CA12CA9ERN1
SCHEMBL29921916 0.67 ALDH1A1 (0.48) CA1CA2CA9
SCHEMBL1538062 0.67 GAA (0.43) CA1CA12CA9ERN1
SCHEMBL822479 0.67 CYP1A2 (0.53) NNMTERN1
SCHEMBL2294952 0.66 ALDH1A1 (0.48) ACP1
Trifluoromethanesulfonic Acid SCHEMBL25330258 0.65 HDAC8 (0.43) KDR
SCHEMBL30578752 0.64 MMP3 (0.55) KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001475-A CONTINUOUS PHASE OF POLY(P-PHENYLENE TEREPHTHALAMIDE) AND DISPERSED THEREIN DOMAINS OF SULFONATED POLYANILINE HAVING SILVER PARTICLES INTERMINGLED; CAN BE SILVER PLATED WITHOUT CHEMICAL TREATMENT; ELECTROCONDUCTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-12-14 US disclosed