Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657936 | 0.82 | GPR3 (0.50) | GPR3KDM4ECYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL7836462 | 0.81 | GPR3 (0.42) | GPR3PARP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7823737 | 0.81 | GPR3 (0.42) | GPR3PARP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8676184 | 0.81 | GPR3 (0.42) | GPR3PARP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL19751006 | 0.75 | TLR8 (0.54) | PARP1KDM4ECYP3A4TSHRHSD17B10 | |
| SCHEMBL27832687 | 0.72 | KDM4E (0.58) | PARP1KDM4ECYP1A2CYP3A4TSHR | |
| SCHEMBL29539238 | 0.71 | KMT2A (0.56) | GPR3PARP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7546417 | 0.71 | ALDH1A1 (0.51) | PARP1KDM4ECYP1A2CYP3A4TSHR | |
| SCHEMBL3731476 | 0.71 | KDM4E (0.78) | PARP1KDM4ECYP1A2CYP3A4TSHR | |
| SCHEMBL2312001 | 0.70 | ALDH1A1 (0.41) | PARP1KDM4ETSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |