Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9962959 | 0.84 | LMNA (0.60) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL28515962 | 0.80 | TSHR (0.59) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL16868509 | 0.79 | LMNA (0.54) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL339572 | 0.77 | LMNA (1.00) | LMNATSHRHPGDGAACYP3A4 | |
| Pyrophosphoric Acid SCHEMBL28579050 | 0.77 | LMNA (0.56) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL109490 | 0.77 | LMNA (0.71) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL3888844 | 0.77 | LMNA (0.52) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL28351599 | 0.77 | LMNA (0.52) | LMNATSHRHPGDGAACYP3A4 | |
| SCHEMBL11813178 | 0.76 | MMP2 (0.41) | LMNATSHRCA12CA1MMP8 | |
| P-Xylene SCHEMBL28910761 | 0.76 | LMNA (0.68) | LMNATSHRHPGDGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811188-A | FOR DIELECTRICS, PREPREGS OR OTHER ELECTRICAL EQUIPMEWNT | SIEMENS AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |
| EP-0773968-A1 | PHOSPHORUS-MODIFIED EPOXIDE RESINS, PROCESS FOR PRODUCING THE SAME AND THEIR USE | SIEMENS AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004327-A1 | PHOSPHORUS-MODIFIED EPOXIDE RESINS, PROCESS FOR PRODUCING THE SAME AND THEIR USE | SIEMENS AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |