Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615047 | 0.78 | ANPEP (0.44) | KDM4ELMNAMAPK1ANPEPERAP1 | |
| SCHEMBL7953179 | 0.77 | ANPEP (0.47) | KDM4ELMNAMAPK1ANPEPERAP1 | |
| SCHEMBL4714858 | 0.77 | SLC6A2 (0.48) | ANPEPERAP1ERAP2HTR2ASIGMAR1 | |
| SCHEMBL8409870 | 0.70 | ANPEP (0.49) | ANPEPERAP1ERAP2TSHR | |
| Hydrochloric Acid SCHEMBL7836848 | 0.69 | ANPEP (0.47) | ANPEPERAP1ERAP2TSHR | |
| SCHEMBL6112090 | 0.69 | ANPEP (0.41) | KDM4ELMNAMAPK1ANPEPERAP1 | |
| SCHEMBL28619892 | 0.68 | GRIK1 (0.44) | ANPEPERAP1ERAP2HTR2AIDO1 | |
| SCHEMBL7465282 | 0.67 | CES1 (0.46) | ANPEPERAP1ERAP2TSHR | |
| SCHEMBL2124923 | 0.67 | TSHR (0.48) | KDM4ECYP1A2TSHRCYP2C19 | |
| SCHEMBL894528 | 0.67 | SLC6A2 (0.60) | ANPEPERAP1ERAP2HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10330331-A | — | — | None | — | — | JP | disclosed |
| JP-H10330331-A | PRODUCTION OF DEXFENFLURAMINE HYDROCHLORIDE | PIEFETI IT SRL | 1998-12-15 | — | — | JP | disclosed |