Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674172 | 0.83 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CKCNN4 | |
| Hydrochloric Acid SCHEMBL8674349 | 0.81 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL8671482 | 0.71 | ABHD6 (0.37) | ADRA2AADRA2BADRA2CABHD6HSD17B3 | |
| SCHEMBL8670854 | 0.71 | CYP1A2 (0.50) | ADRA2AADRA2BADRA2CABHD6HSD17B3 | |
| SCHEMBL14306400 | 0.68 | HSD17B3 (0.49) | ADRA2AADRA2BADRA2CABHD6HSD17B3 | |
| SCHEMBL8674126 | 0.67 | TIPARP (0.42) | ADRA2AADRA2BADRA2CTMEM97SIGMAR1 | |
| SCHEMBL8677169 | 0.67 | CYP1A2 (0.55) | ADRA2AADRA2BADRA2CCYP17A1CYP21A2 | |
| Hydrochloric Acid SCHEMBL8675249 | 0.66 | TIPARP (0.41) | ADRA2AADRA2BADRA2CTMEM97SIGMAR1 | |
| SCHEMBL961792 | 0.66 | KCNN4 (0.44) | ADRA2AADRA2BADRA2CKCNN4HDAC3 | |
| SCHEMBL27260114 | 0.65 | NISCH (0.46) | ADRA2AADRA2BADRA2CKCNN4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |