Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8674349 | 0.98 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CKCNN4ALDH1A1 | |
| SCHEMBL8676334 | 0.83 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL8677169 | 0.81 | CYP1A2 (0.55) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL8674126 | 0.81 | TIPARP (0.42) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8673745 | 0.80 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8675249 | 0.80 | TIPARP (0.41) | ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8670817 | 0.79 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CALDH1A1HRH4 | |
| SCHEMBL5658841 | 0.72 | — | — | |
| SCHEMBL8674232 | 0.71 | MAPT (0.42) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL8675140 | 0.71 | ADRA2B (0.37) | ADRA2AADRA2BADRA2CKCNN4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |