Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438167 | 0.85 | TSHR (0.56) | KDM4EPOLBMEN1KMT2ATAAR1 | |
| SCHEMBL3440495 | 0.79 | MAPT (0.64) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3440494 | 0.79 | MAPT (0.64) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30383352 | 0.79 | MAPT (0.64) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8675291 | 0.78 | FDPS (0.61) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29426332 | 0.78 | FDPS (0.61) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29711664 | 0.75 | FDPS (0.64) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8676380 | 0.75 | MEN1 (0.53) | KDM4EMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL11762781 | 0.75 | CASR (0.52) | KDM4EMEN1KMT2AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11870429 | 0.74 | MAPT (0.52) | KDM4EMEN1KMT2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804603-A | ADMINISTERING AS HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION; TOXICITY; LOWERS BLOOD PRESSURE. | NATIONAL SCIENCE COUNCIL (TW) | 1998-09-08 | — | — | US | disclosed |