Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426332 | 1.00 | FDPS (0.61) | FDPSAPPKMT2AMEN1PTGES | |
| SCHEMBL29711664 | 0.88 | FDPS (0.64) | FDPSKMT2AMEN1NFE2L2KDM4E | |
| SCHEMBL8674631 | 0.86 | FDPS (0.62) | FDPSAPPKMT2AMEN1PTGES | |
| SCHEMBL7682835 | 0.83 | NFE2L2 (0.54) | FDPSKMT2AMEN1NFE2L2KDM4E | |
| SCHEMBL3440495 | 0.83 | MAPT (0.64) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30383352 | 0.83 | MAPT (0.64) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3440494 | 0.83 | MAPT (0.64) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8438167 | 0.78 | TSHR (0.56) | KMT2AMEN1KDM4E | |
| SCHEMBL8676376 | 0.78 | KDM4E (0.50) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11022622 | 0.77 | FDPS (0.65) | FDPSKMT2AMEN1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804603-A | ADMINISTERING AS HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION; TOXICITY; LOWERS BLOOD PRESSURE. | NATIONAL SCIENCE COUNCIL (TW) | 1998-09-08 | — | — | US | disclosed |