SCHEMBL867649

SCHEMBL867649

C=CC(=O)OCCCCCC(C)CCCCCCCC

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.66
HPGD P15428 1/20 0.66
ALDH1A1 P00352 3/20 0.61
CYP3A4 P08684 1/20 0.61
HCAR2 Q8TDS4 3/20 0.50
ACE2 Q9BYF1 1/20 0.49
ATM Q13315 1/20 0.46
NAAA Q02083 1/20 0.44
TP53 P04637 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 1/20 0.43
EPHX1 P07099 1/20 0.42
ABCB1 P08183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650159 1.00 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL651659 1.00 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL31742400 0.95 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL31742399 0.95 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL31742401 0.94 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL10615420 0.94 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL11529650 0.92 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL3190479 0.90 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6142430 0.90 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL9651160 0.90 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-20180320072-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
US-20180319939-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
EP-3374467-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
EP-3374416-A1 PHOTOALIGNMENT MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 TSHR 4828/4885HPGD 1068/4885ALDH1A1 97/4885
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 TSHR 4828/4885HPGD 1068/4885ALDH1A1 97/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD TSHR 3933/4885HPGD 852/4885ALDH1A1 313/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 TSHR 4598/4885HPGD 3943/4885ALDH1A1 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.