Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522725 | 0.87 | PTGER1 (0.56) | MRGPRX4PTGER1TDP1PTGER4PTGER3 | |
| SCHEMBL8675455 | 0.85 | ESR1 (0.52) | PTGER1TDP1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676624 | 0.83 | MRGPRX4 (0.48) | MRGPRX4PTGER1TDP1PTGER4PTGER3 | |
| SCHEMBL8675900 | 0.83 | TDP1 (0.48) | PTGER1TDP1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676387 | 0.82 | PTGER1 (0.62) | PTGER1TDP1PTGER4PTGER3PTGER2 | |
| SCHEMBL8326500 | 0.81 | PTGER1 (0.69) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676634 | 0.81 | MTNR1B (0.57) | MRGPRX4TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL8676443 | 0.80 | PTGER1 (0.51) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8675525 | 0.79 | PTGER1 (0.61) | PTGER1TDP1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677127 | 0.79 | RAB9A (0.56) | KMT2APPIACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |