Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880786 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRKCNN4CYP2A6CYP2C19 | |
| SCHEMBL10538145 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KCNN4CYP2A6KMT2AMEN1 | |
| SCHEMBL31620694 | 0.86 | KIF11 (0.42) | ALDH1A1TSHRCYP2C19HIF1ACYP1A2 | |
| SCHEMBL11723215 | 0.82 | TSHR (0.50) | ALDH1A1TSHRCYP2A6CYP3A4KMT2A | |
| SCHEMBL11755159 | 0.81 | KIF11 (0.44) | TSHRCYP2C19CYP3A4KMT2AMEN1 | |
| SCHEMBL548046 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRKCNN4CYP2A6CYP1A2 | |
| SCHEMBL3522115 | 0.78 | KCNN4 (0.52) | ALDH1A1TSHRKCNN4CYP2A6CYP2C19 | |
| SCHEMBL1933521 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRKCNN4CYP2A6CYP1A2 | |
| SCHEMBL27596588 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRKCNN4CYP2A6CYP1A2 | |
| SCHEMBL1414647 | 0.74 | ESR1 (0.41) | ALDH1A1TSHRKCNN4CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524359-B | A kind of with three big steric hindrance substituting group C2Symmetrical optically-active aminodiol and preparation method and purposes | 湘潭大学 | 2016-06-08 | — | — | CN | claimed |
| US-9029501-B2 | Method for making macrocycles | RIGEL PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | claimed |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | US | claimed |
| WO-2012061408-A2 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS. INC. (US) | 2012-05-10 | — | — | WO | claimed |
| US-5061795-A | ANTITUMOR AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | claimed |
| US-4534898-A | 1-Oxa-1-dethia-cephalosporin derivatives | MERCK & CO., INC. (US) | 1985-08-13 | — | — | US | claimed |
| CN-113508126-B | Novel peptides and uses thereof | 因首生物科学有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023090686-A1 | PENTAPEPTIDE AND USE THEREOF | ENSOL BIOSCIENCES INC. (KR) | 2023-05-25 | — | — | WO | disclosed |
| CN-109476702-B | Peptides and uses thereof | 因首生物科学有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-113508126-A | Novel peptides and uses thereof | 因首生物科学有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-107787325-B | Novel peptides and uses thereof | 因首生物科学有限公司 | 2021-09-10 | — | — | CN | disclosed |
| WO-2019013814-A1 | 3-D PRINTING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2019-01-17 | — | — | WO | disclosed |
| CN-108697713-A | Methods for making tricyclic PI3K inhibitor compounds and methods of treating cancer therewith | 基因泰克公司 | 2018-10-23 | — | — | CN | disclosed |
| US-4065623-A | O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4044060-A | PHOSGENE, THIONYL, PHOSPHORUS, ALDEHYDE, KETONE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-23 | — | — | US | disclosed |
| US-4039413-A | OXYGEN-FREE, UV OR VISIBLE LIGHT, ORGANIC PEROXIDE, ACRYLIC POLYMERSON | ROHM GMBH (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4014872-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (EN) | 1977-03-29 | — | — | US | disclosed |
| US-4013648-A | BETA-LACTAM ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012383-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4011216-A | Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | EZR, SQLE, CBR3 | ALDH1A1 1812/4885TSHR 3677/4885KCNN4 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.