Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528030 | 0.91 | ALDH1A1 (0.43) | ESR1ESR2ALDH1A1KCNN4CYP2A6 | |
| SCHEMBL5255832 | 0.89 | ESR1 (0.59) | ESR1ESR2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL21495110 | 0.89 | KIF11 (0.43) | ESR1ESR2ALDH1A1TSHRCYP2A6 | |
| SCHEMBL8796837 | 0.89 | KIF11 (0.43) | TSHRCYP1A2KMT2AMEN1LMNA | |
| SCHEMBL4015306 | 0.89 | KCNN4 (0.50) | ALDH1A1TSHRKCNN4KMT2AMEN1 | |
| SCHEMBL10922195 | 0.82 | CYP19A1 (0.47) | CYP1A2CYP3A4LMNATDP1 | |
| SCHEMBL8813777 | 0.82 | KIF11 (0.50) | — | |
| Bromide SCHEMBL10923256 | 0.80 | CYP19A1 (0.46) | CYP1A2CYP3A4KMT2AMEN1LMNA | |
| SCHEMBL10923959 | 0.79 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL548046 | 0.77 | ALDH1A1 (0.43) | ESR1ESR2ALDH1A1TSHRKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683981-B | Ketone-containing controllable radical initiator for polymerization | 3M创新有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111683981-A | Ketone-containing controlled radical initiators for polymerization reactions | 3M创新有限公司 | 2020-09-18 | — | — | CN | disclosed |
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |
| US-7018431-B2 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2004-05-20 | — | — | US | disclosed |
| EP-1408090-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1339798-A2 | SULFONATED DIARYLRHODAMINE DYES | Applera Corporation (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6583168-B1 | Fluorescent labels of nucleosides, nucleotides, polynucleotides, and polypeptides in nucleic acid analysis | APPLERA CORPORATION | 2003-06-24 | — | — | US | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-0656893-B1 | PHOTOCHROMIC OXAZINE COMPOUNDS | RODENSTOCK OPTIK G (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-1034221-A1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6051719-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999027020-A1 | DIBENZORHODAMINE DYES USEFUL AS FLOURESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5801243-A | REACTING A SUBSTITUTED ALDEHYDE WITH A SUBSTITUTED ORTHO-AMINO-HYDROXY AROMATIC COMPOUND | OPTISCHE WERKE G. RODENSTOCK (DE) | 1998-09-01 | — | — | US | disclosed |
| EP-0656893-A1 | PHOTOCHROMIC OXAZINE COMPOUNDS | Optische Werke G. Rodenstock (DE) | 1995-06-14 | — | — | EP | disclosed |
| WO-1995000500-A1 | PHOTOCHROMIC OXAZINE COMPOUNDS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | POLL, DUT, DPYD | ESR1 2974/4885ESR2 3028/4885ALDH1A1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.