Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679119 | 0.82 | TLR7 (0.40) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| SCHEMBL8678081 | 0.81 | TLR7 (0.40) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| SCHEMBL8678688 | 0.81 | KDM5B (0.40) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| SCHEMBL8678941 | 0.78 | TLR7 (0.38) | L3MBTL1TLR7SMN1; SMN2LMNANPSR1 | |
| SCHEMBL8677187 | 0.77 | TLR7 (0.37) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| SCHEMBL18176612 | 0.71 | ALDH1A1 (0.65) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| Fluoromethane SCHEMBL27480458 | 0.71 | ALPL (0.43) | TLR7SMN1; SMN2LMNARAB9AMEN1 | |
| SCHEMBL8680407 | 0.70 | KDM5A (0.41) | SMN1; SMN2NPSR1MEN1HTTKMT2A | |
| SCHEMBL8678948 | 0.69 | TLR7 (0.44) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A | |
| SCHEMBL8680415 | 0.69 | TLR7 (0.42) | L3MBTL1TLR7SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |