Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678688 | 0.87 | KDM5B (0.40) | TLR7L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8679119 | 0.86 | TLR7 (0.40) | TLR7L3MBTL1ALDH1A1NPSR1MEN1 | |
| SCHEMBL8678081 | 0.85 | TLR7 (0.40) | TLR7L3MBTL1ALDH1A1NPSR1MEN1 | |
| SCHEMBL8676871 | 0.78 | L3MBTL1 (0.41) | TLR7L3MBTL1ALDH1A1NPSR1MEN1 | |
| SCHEMBL8680407 | 0.76 | KDM5A (0.41) | NPSR1MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8677229 | 0.75 | KDM5B (0.37) | — | |
| SCHEMBL8677187 | 0.75 | TLR7 (0.37) | TLR7L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8677070 | 0.74 | KDM5B (0.39) | ALDH1A1KDM4EHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL8681283 | 0.74 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EHSD17B10CYP2C9 | |
| SCHEMBL8127133 | 0.73 | NPSR1 (0.37) | TLR7L3MBTL1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| CN-1109879-A | 2-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1995-10-11 | — | — | CN | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |