Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678794 | 0.99 | GRM2 (0.47) | GRM2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8678028 | 0.96 | GRM2 (0.45) | GRM2ITGB3ITGA2BFFAR1S1PR1 | |
| SCHEMBL8679817 | 0.93 | GRM2 (0.43) | GRM2ITGB3FFAR1PTGESALOX5 | |
| SCHEMBL8676560 | 0.85 | FNTA (0.41) | ITGB1ITGA4 | |
| SCHEMBL8676384 | 0.83 | GPR132 (0.43) | — | |
| SCHEMBL8679794 | 0.82 | PPARG (0.43) | GRM2PPARG | |
| SCHEMBL8679534 | 0.82 | PTPN1 (0.46) | ITGB3PPARGITGB1MEN1KMT2A | |
| SCHEMBL8675834 | 0.81 | FNTA (0.41) | GRM2ITGB3PTGESALOX5PPARG | |
| SCHEMBL8678019 | 0.81 | PPARG (0.45) | GRM2PPARG | |
| SCHEMBL8677140 | 0.81 | SRD5A2 (0.45) | GRM2ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |