Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TNKS | O95271 | 6/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677237 | 0.80 | XDH (0.68) | KMT2AALDH1A1L3MBTL1HPGDTNKS | |
| SCHEMBL8678923 | 0.78 | KDM4E (0.48) | KMT2AALDH1A1HSP90AA1HTTNPSR1 | |
| SCHEMBL9006008 | 0.75 | HPGD (0.50) | ALDH1A1L3MBTL1HPGDTNKSTNKS2 | |
| SCHEMBL5383503 | 0.74 | MAPK13 (0.60) | ALDH1A1HPGDPOLBMAPTCYP1A2 | |
| SCHEMBL8677247 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1HPGDTNKSTNKS2POLB | |
| SCHEMBL655574 | 0.73 | HPGD (0.49) | KMT2AALDH1A1L3MBTL1HPGDTNKS | |
| SCHEMBL7184765 | 0.71 | HPGD (0.47) | KMT2AALDH1A1HTTNPSR1HPGD | |
| SCHEMBL649956 | 0.70 | HPGD (0.45) | HPGDTNKSTNKS2WNT3ACYP1A2 | |
| SCHEMBL23414938 | 0.69 | ALDH1A1 (0.48) | KMT2AALDH1A1HSP90AA1HTTNPSR1 | |
| SCHEMBL17959973 | 0.69 | ALDH1A1 (0.48) | KMT2AALDH1A1HSP90AA1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0579424-B1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| CN-1109879-A | 2-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1995-10-11 | — | — | CN | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| CN-1084165-A | 2-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-03-23 | — | — | CN | disclosed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |