SCHEMBL8677276

SCHEMBL8677276

CC(=O)O[Cu].CCN(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.39
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TRPA1 O75762 1/20 0.32
PAOX Q6QHF9 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1886128 0.80 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNACHRM2CHRM4
Acetic Acid Methyl Ester SCHEMBL10776169 0.80 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNACHRM2CHRM4
SCHEMBL1886127 0.80 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNACHRM2CHRM4
Acetone SCHEMBL3715272 0.78 LMNA (0.46) ALDH1A1HSD17B10LMNACHRM2CHRM4
SCHEMBL221318 0.78
Methyl Alcohol SCHEMBL8398762 0.78 ALDH1A1 (0.56) ALDH1A1HSD17B10LMNACHRM2CHRM4
Ethyl Acetate SCHEMBL6046507 0.76 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNACHRM2CHRM4
Ethyl Acetate SCHEMBL276158 0.76 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNACHRM2CHRM4
Ethyl Acetate SCHEMBL5861342 0.76 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNACHRM2CHRM4
Ethyl Acetate SCHEMBL6347449 0.76 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723539-A POLYMER BLEND WITH POLYCARBOXYLIC ACID FOR IMPACT STRENGTH, CHEMICAL RESISTANCE AND PROCESSABILITY GENERAL ELECTRIC (US) 1998-03-03 US disclosed
US-5719233-A BLEND ALSO CONTAINING (PARTIALLY) HYDROGENATED VINYL AROMATIC CONJUGATED DIENE BLOCK POLYMER AND ONE OR MORE ALIPHATIC POLYCARBOXYLIC ACIDS OR ESTER OR AMIDE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 1998-02-17 US disclosed
US-5461096-A Nondripping GENERAL ELECTRIC COMPANY (US) 1995-10-24 US disclosed
EP-0504280-B1 Process for preparing a blend comprising a polyester, a polyphenylene oxide and block and/or graft copolymers of the polyester and polyphenylene oxide. ALLIED SIGNAL INC (US) 1995-08-09 EP disclosed
US-5428091-A Curable blends for molding, shaping; chemical resistance, mechanical properties SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-27 US disclosed
EP-0485598-B1 THERMOPLASTIC RESIN COMPOSITION SUMITOMO CHEMICAL CO (JP) 1995-04-12 EP disclosed
US-5338796-A Thermoplastic composition based on polyphenylene ether and polyamide MONTEDIPE S.R.L. (IT) 1994-08-16 US disclosed
US-5336732-A Dispersing polyphenylene ether in polyamide matrix ALLIEDSIGNAL INC. 1994-08-09 US disclosed
EP-0355122-B1 COMPOSITIONS OF POLYPHENYLENE OXIDES AND THERMOPLASTIC POLYMERS ALLIED SIGNAL INC (US) 1994-07-13 EP disclosed
US-5300568-A Blend containing dinitrodiamine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-05 US disclosed
US-4642358-A POLYAMIDES, POLYESTERS GENERAL ELECTRIC COMPANY (US) 1987-02-10 US disclosed
US-4600741-A ACYL MODIFIED POLYPHENYLENE ETHER AS COMPATIBILIZATION AGENT GENERAL ELECTRIC COMPANY (US) 1986-07-15 US disclosed
EP-0185054-A1 GEN ELECTRIC 1986-06-25 EP disclosed
EP-0182163-A2 Silane derivatives which improve the properties of polyphenylene oxide-polyamide compositions GENERAL ELECTRIC COMPANY (US) 1986-05-28 EP disclosed
WO-1986002086-A1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1986-04-10 WO disclosed
WO-1985005372-A1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS AND PROCESS GENERAL ELECTRIC COMPANY (US) 1985-12-05 WO disclosed
EP-0024120-B1 RESIN COMPOSITIONS COMPRISING POLYPHENYLENE OXIDE, POLYAMIDE AND A COMPOUND IMPROVING THE IMPACT RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-04-06 EP disclosed
US-4338421-A BLEND OF POLYPHENYLENE ETHER AND POLYLACTAM OR POLYAMIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US disclosed
US-4315086-A POLYPHENYLENE ETHER, POLYAMIDE, SOLVENT AND IMPACT RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-02-09 US disclosed
EP-0024120-A1 Resin compositions comprising polyphenylene oxide, polyamide and a compound improving the impact resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-02-25 EP disclosed