Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405800 | 0.85 | TSHR (0.39) | TSHRMAPTKMT2ALMNACYP1A2 | |
| SCHEMBL7253138 | 0.82 | PDE2A (0.43) | TSHRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL11281234 | 0.81 | ESR1 (0.43) | TSHRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL465848 | 0.81 | TSHR (0.52) | TSHRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6563424 | 0.79 | TSHR (0.37) | TSHRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL678316 | 0.77 | KMT2A (0.52) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11116753 | 0.77 | TSHR (0.36) | TSHRMAPTNPC1RAB9AHDAC1 | |
| SCHEMBL56361 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL45199 | 0.77 | MEN1 (0.41) | TSHRMEN1KMT2ALMNAHPGD | |
| SCHEMBL9471595 | 0.76 | SLC2A1 (0.44) | TSHRMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240052109-A1 | POLYSILOXANE VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2024-02-15 | — | — | US | disclosed |
| US-5719096-A | ISOMER BLEND; CROSSLINKING POLYMERS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5539061-A | FOR CROSSLINKING THERMOPLASTIC RESINS, POLYETHYLENE, ETHYLENE-PROPYLENE COPOLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0088218-A1 | Preparation of tertiary alkyl isocyanates | AMERICAN CYANAMID COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| US-4399074-A | FROM THE HALIDE, CATALYST COMPLEX OF ZINC SALT, PYRIDINE AND ALKALI METAL CYANATE | AMERICAN CYANAMID COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4399073-A | FROM THE HALIDE AND ALKALI METAL CYANATE, WATER | AMERICAN CYANAMID COMPANY (US) | 1983-08-16 | — | — | US | disclosed |