Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677283 | 0.82 | TSHR (0.36) | TSHRMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL465848 | 0.81 | TSHR (0.52) | TSHRMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL11281234 | 0.81 | ESR1 (0.43) | TSHRMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL1474670 | 0.79 | CES2 (0.54) | NR4A1NR4A2NR4A3SRD5A2CES2 | |
| SCHEMBL6563424 | 0.79 | TSHR (0.37) | TSHRMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL11116753 | 0.77 | TSHR (0.36) | TSHRMAPTHDAC1NPC1RAB9A | |
| SCHEMBL8349213 | 0.77 | EPHX2 (0.47) | PDE2AMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL1706121 | 0.77 | PDE2A (0.62) | PDE2ATSHRAKT1AKT2MEN1 | |
| SCHEMBL56361 | 0.77 | MAPT (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL34472322 | 0.77 | PDE2A (0.44) | PDE2AAKT1AKT2NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340976-B1 | Acrylic polymers | PPG INDUSTRIES INC (US) | 1995-06-28 | — | — | EP | claimed |
| US-5098974-A | Protective coatings containing pigments | PPG INDUSTRIES, INC. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0340976-A2 | Acrylic polymers | PPG INDUSTRIES, INC. (US) | 1989-11-08 | — | — | EP | claimed |
| EP-0127802-B1 | META- AND PARA-ISOPROPENYL-ALPHA,ALPHA-DIMETHYLBENZYLAMINE | AMERICAN CYANAMID COMPANY (US) | 1988-04-20 | — | — | EP | claimed |
| US-4547265-A | Method for sizing paper using hydrolyzed homopolymers or copolymers of meta- or para- isopropenyl-α,α-dimethylbenzylisocyanate | AMERICAN CYANAMID COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| EP-0127802-A2 | Meta- and para-isopropenyl-alpha,alpha-dimethylbenzylamine | AMERICAN CYANAMID COMPANY (US) | 1984-12-12 | — | — | EP | claimed |
| JP-1092227-A | — | — | None | — | — | JP | disclosed |
| JP-63218714-A | — | — | None | — | — | JP | disclosed |
| US-6630599-B1 | Blocked derivatives of m- or p- isopropenyl- alpha , alpha -dimethylbenzyl isocyanates, comprising reacting a meta- or a para-isopropenyl-alpha, alpha-dimethylbenzyl carbamate ester with hydroxy functional blocking group, such as | CYTEC TECHNOLOGY CORP. | 2003-10-07 | — | — | US | disclosed |
| EP-0340976-B1 | Acrylic polymers | PPG INDUSTRIES INC (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5098974-A | Protective coatings containing pigments | PPG INDUSTRIES, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4927969-A | Preparation of alkyl primary amines | PPG INDUSTRIES, INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4910249-A | Containing a tertiary alkyl primary amine group | PPG INDUSTRIES, INC. (US) | 1990-03-20 | — | — | US | disclosed |
| JP-S63218714-A | COPOLYMER HAVING AMINO GROUP ON SIDE CHAIN AND PRODUCTION THEREOF | TAKEDA CHEM IND LTD | 1988-09-12 | — | — | JP | disclosed |
| EP-0127802-B1 | META- AND PARA-ISOPROPENYL-ALPHA,ALPHA-DIMETHYLBENZYLAMINE | AMERICAN CYANAMID COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4547265-A | Method for sizing paper using hydrolyzed homopolymers or copolymers of meta- or para- isopropenyl-α,α-dimethylbenzylisocyanate | AMERICAN CYANAMID COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| US-4547265-A | Method for sizing paper using hydrolyzed homopolymers or copolymers of meta- or para- isopropenyl-α,α-dimethylbenzylisocyanate | AMERICAN CYANAMID COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0127802-A2 | Meta- and para-isopropenyl-alpha,alpha-dimethylbenzylamine | AMERICAN CYANAMID COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| EP-0127802-A2 | Meta- and para-isopropenyl-alpha,alpha-dimethylbenzylamine | AMERICAN CYANAMID COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| EP-0127802-A2 | Meta- and para-isopropenyl-alpha,alpha-dimethylbenzylamine | AMERICAN CYANAMID COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |