SCHEMBL8677464

SCHEMBL8677464

CC(C)c1ccc(-c2ccccc2)c(C(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
PTGS1 P23219 3/20 0.44
MEN1 O00255 2/20 0.44
PTGS2 P35354 2/20 0.44
KMT2A Q03164 2/20 0.44
FABP2 P12104 1/20 0.44
TSHR P16473 1/20 0.44
AKR1C4 P17516 1/20 0.44
ADRA2B P18089 1/20 0.44
CHRM3 P20309 1/20 0.44
HTR2C P28335 1/20 0.44
DRD3 P35462 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676137 0.88 LMNA (0.48) LMNAPTGS1MEN1KMT2AMAPT
SCHEMBL17810080 0.87 RXRA (0.38) LMNAPTGS1MEN1PTGS2KMT2A
SCHEMBL8675449 0.86 RXRA (0.45) LMNAAKR1C3AKR1C2CYP1A2MAPT
SCHEMBL3293062 0.84 LMNA (0.45) LMNAPTGS1MEN1PTGS2KMT2A
SCHEMBL10878363 0.83 LMNA (0.54) LMNAPTGS1MEN1PTGS2KMT2A
SCHEMBL1485527 0.82 ROCK2 (0.41) LMNAPTGS1MEN1PTGS2KMT2A
SCHEMBL22589014 0.82 MEN1 (0.47) LMNAMEN1PTGS2KMT2AMAPT
SCHEMBL30103901 0.82 LMNA (0.47) LMNAPTGS1MEN1KMT2ATSHR
SCHEMBL16050343 0.82 LMNA (0.47) LMNAPTGS1MEN1KMT2ATSHR
SCHEMBL28347509 0.81 LMNA (0.42) LMNAPTGS1HIF1APDK2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108424423-A Heteroleptic iridium complex 通用显示公司 2018-08-21 CN disclosed
CN-108164565-A Heteroleptic iridium complex 通用显示公司 2018-06-15 CN disclosed
US-5847040-A Lower alkyl biphenyls as plasticizers for polyurethane KOCH INDUSTRIES, INC. (US) 1998-12-08 US disclosed
US-5696184-A EPOXY POLYMER CONTAINING DIISOPROPYLBIPHENYL AND/OR TRIISOPROPYLBIPHENYL; INCREASED FLEXIBILITY AND TOUGHNESS KOCH INDUSTRIES, INC. (US) 1997-12-09 US disclosed
US-5489646-A CAN USE HIGH LOAD LEVELS KOCH INDUSTRIES, INC. (US) 1996-02-06 US disclosed
US-4266264-A FOIL CAPACITORS WESTINGHOUSE ELECTRIC CORP. (US) 1981-05-05 US disclosed