Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orcinol SCHEMBL4458019 | 0.90 | ALDH1A1 (0.43) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| SCHEMBL27742783 | 0.89 | ACHE (0.54) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| Resorcinol SCHEMBL37801 | 0.88 | ALDH1A1 (0.52) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| Resorcinol SCHEMBL28826037 | 0.88 | ALDH1A1 (0.52) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| SCHEMBL28261511 | 0.87 | ALDH1A1 (0.47) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| Hydroquinone SCHEMBL50263 | 0.86 | TSHR (0.48) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| Resorcinol SCHEMBL27815945 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| SCHEMBL4198438 | 0.86 | TSHR (0.41) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| SCHEMBL27761106 | 0.85 | ACHE (0.48) | TSHRALDH1A1TP53SMN1; SMN2HIF1A | |
| Resorcinol SCHEMBL3731090 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1TP53SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120041182-A | Particle size-controllable epoxy resin fracturing propping agent and preparation method thereof | 江苏扬农化工集团有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119752183-A | Preparation method of epoxy resin fracturing propping agent with high heat resistance and low breakage rate | 江苏扬农化工集团有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119220152-A | Steel structure roof waterproof paint and preparation method thereof | 中铁十八局集团有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-111534260-A | Epoxy resin packaging adhesive and preparation method and application thereof | 北京康美特科技股份有限公司 | 2020-08-14 | — | — | CN | claimed |
| EP-4743503-A1 | DUAL CURABLE OLIGOMERS | ARKEMA France (FR) | 2026-05-20 | — | — | EP | disclosed |
| CN-120041182-A | Particle size-controllable epoxy resin fracturing propping agent and preparation method thereof | 江苏扬农化工集团有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119752183-A | Preparation method of epoxy resin fracturing propping agent with high heat resistance and low breakage rate | 江苏扬农化工集团有限公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2025012243-A1 | DUAL CURABLE OLIGOMERS | ARKEMA FRANCE (FR) | 2025-01-16 | — | — | WO | disclosed |
| EP-4491649-A1 | DUAL CURABLE OLIGOMERS | ARKEMA FRANCE (FR) | 2025-01-15 | — | — | EP | disclosed |
| CN-119220152-A | Steel structure roof waterproof paint and preparation method thereof | 中铁十八局集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-112322237-A | Single-component UV (ultraviolet) delayed curing adhesive composition and preparation and application methods thereof | 江南大学 | 2021-02-05 | — | — | CN | disclosed |
| US-8828268-B2 | Use of molecules having associative groups as hardeners for thermosetting resins | ARKEMA FRANCE (FR) | 2014-09-09 | — | — | US | disclosed |
| US-20130274432-A1 | Use of Molecules Having Associative Groups As Hardeners for Thermosetting Resins | ARKEMA FRANCE (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20130248087-A1 | PROCESS FOR PRODUCING FIBROUS MATERIAL PRE-IMPREGNATED WITH THERMOSETTING POLYMER | ARKEMA FRANCE (FR) | 2013-09-26 | — | — | US | disclosed |
| US-20120074353-A1 | USE OF MOLECULES HAVING ASSOCIATIVE GROUPS AS HARDENERS FOR THERMOSETTING RESINS | ARKEMA FRANCE (FR) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120074353-A1 | USE OF MOLECULES HAVING ASSOCIATIVE GROUPS AS HARDENERS FOR THERMOSETTING RESINS | NES, NBAS, HDAC10 | TSHR 4440/4885ALDH1A1 2439/4885TP53 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.