Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874305 | 0.79 | LMNA (0.36) | LMNAALDH1A1 | |
| SCHEMBL3905334 | 0.76 | ALDH1A1 (0.32) | LMNAALDH1A1CA2 | |
| SCHEMBL28057144 | 0.74 | ALDH1A1 (0.42) | LMNAALDH1A1 | |
| SCHEMBL112469 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL630048 | 0.72 | LMNA (0.40) | LMNAALDH1A1CA2 | |
| SCHEMBL584638 | 0.71 | — | — | |
| Water SCHEMBL5127632 | 0.71 | LMNA (0.37) | LMNAALDH1A1CA2 | |
| Trifluoroacetic Acid SCHEMBL28287909 | 0.71 | LMNA (0.62) | LMNAALDH1A1CA2 | |
| Water SCHEMBL7929821 | 0.71 | LMNA (0.37) | LMNAALDH1A1CA2 | |
| SCHEMBL6908016 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349183-A | Preparation method for 2-methyl-4-trifluoromethyl-5-febuxostat | 青岛瀚生生物科技股份有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-116354902-A | Green and environment-friendly process for synthesizing 2-methyl-4-trifluoromethyl-5-thiazole formic acid | 广东禾康精细化工有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-106905153-B | Method for preparing 2-chloro-4,4, 4-trifluoroacetylacetic acid ethyl ester by continuous non-catalytic reaction | 浙江蓝天环保高科技股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| EP-3658701-A1 | PROCESS FOR THE PREPARATION OF METALLIC NANO-PARTICLE LAYERS AND THEIR USE FOR DECORA-TIVE OR SECURITY ELEMENTS | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| WO-2019020682-A1 | PROCESS FOR THE PREPARATION OF METALLIC NANO-PARTICLE LAYERS AND THEIR USE FOR DECORA-TIVE OR SECURITY ELEMENTS | BASF SE (DE) | 2019-01-31 | — | — | WO | disclosed |
| CN-106905153-A | A kind of method that continuous non-catalytic reaction prepares the chloro- 4,4,4- trifluoroacetic ethyl acetoacetates of 2- | 浙江蓝天环保高科技股份有限公司 | 2017-06-30 | — | — | CN | disclosed |
| EP-1954696-B1 | 2-PHENOXY-N-(1,3,4-THIADIZOL-2-YL)PYRIDIN-3-AMINE DERIVATIVES AND RELATED COMPOUNDS AS P2Y1 RECEPTOR INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-23 | — | — | EP | disclosed |
| US-5739394-A | 3,3-dioxy-4,4,4-trifluorobutyric acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0371950-B1 | Substituted thiazoles and their use as fungicides | MONSANTO CO (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5045554-A | Fluoro compounds, rice sheath blight, Basidiomycetes type fungus | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |