Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678258 | 0.79 | LMNA (0.40) | LMNAALDH1A1 | |
| SCHEMBL28057144 | 0.70 | ALDH1A1 (0.42) | LMNAALDH1A1 | |
| SCHEMBL882685 | 0.70 | ALDH1A1 (0.34) | LMNAALDH1A1 | |
| SCHEMBL584638 | 0.67 | — | — | |
| SCHEMBL891818 | 0.67 | THRB (0.32) | THRB | |
| SCHEMBL1793066 | 0.66 | THRB (0.41) | ALDH1A1THRB | |
| SCHEMBL1793069 | 0.66 | THRB (0.41) | ALDH1A1THRB | |
| SCHEMBL27869640 | 0.65 | LMNA (0.32) | LMNA | |
| SCHEMBL2988549 | 0.65 | THRB (0.31) | THRB | |
| SCHEMBL15293930 | 0.65 | THRB (0.35) | ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |