Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.55 |
| ▸ | RXRB | P28702 | 4/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634947 | 1.00 | RXRA (0.55) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL1296121 | 1.00 | RXRA (0.55) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL1635891 | 0.96 | ESR1 (0.55) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL30295452 | 0.93 | ESR1 (0.60) | RXRARXRBSRD5A2ESR1ESR2 | |
| Isophthalic Acid SCHEMBL10494662 | 0.93 | RXRA (0.54) | RXRARXRBSRD5A2NR1H4RXRG | |
| SCHEMBL1041916 | 0.93 | RXRA (0.56) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL29466781 | 0.93 | RXRA (0.56) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL9003758 | 0.90 | ESR1 (0.68) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL9003801 | 0.88 | KIF11 (0.48) | RXRARXRBSRD5A2ESR1ESR2 | |
| SCHEMBL5955919 | 0.87 | ALDH1A1 (0.59) | RXRARXRBSRD5A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716998-A | PARTICLES COMPRISING POLYPROPYLENE RESIN AND DIAMIDE COMPOUND AS BETA-FORM NUCLEATING AGENT | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0790275-A1 | PREFOAMED PARTICLES OF POLYPROPYLENE RESIN AND PROCESS FOR PRODUCING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |