Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603520 | 0.87 | PDCD1 (0.36) | LMNAL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL27474790 | 0.86 | ADRA2A (0.35) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28723777 | 0.86 | PDCD1 (0.35) | LMNAL3MBTL1TP53MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL5695379 | 0.86 | PDCD1 (0.35) | LMNAL3MBTL1TP53MAPK1TDP1 | |
| Chloromethane SCHEMBL5722647 | 0.84 | PDCD1 (0.34) | LMNAL3MBTL1MAPK1TDP1CYP2A6 | |
| SCHEMBL7255779 | 0.80 | PDCD1 (0.34) | LMNAL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL27485116 | 0.78 | EDNRB (0.34) | LMNASYKNPC1RAB9AALDH1A1 | |
| SCHEMBL27476105 | 0.78 | PTGS1 (0.34) | KDM4EHIF1ATGFBR1L3MBTL1TP53 | |
| SCHEMBL8469895 | 0.77 | MAOB (0.38) | LMNAKDM4ECYP1A2HTTMAPK1 | |
| SCHEMBL8469896 | 0.77 | MAOB (0.38) | LMNAKDM4ECYP1A2HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807936-A | Transition metal compound | TARGOR GMBH (DE) | 1998-09-15 | — | — | US | disclosed |