SCHEMBL8679062

SCHEMBL8679062

C[C@H](N)C(=O)OC(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
SLC7A5 Q01650 1/20 0.31
ALOX15 P16050 2/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14486118 1.00 CHRNB2 (0.33) CHRNB2CHRNB4CHRNA3CHRNA4SLC7A5
SCHEMBL995487 0.89 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL27906557 0.89 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL11061010 0.89 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
Serine SCHEMBL16031031 0.88 PDCD1LG2 (0.36) SLC7A5ALOX15BLMPMP22KMT2A
SCHEMBL6130798 0.86 SLC7A5 (0.48) SLC7A5
SCHEMBL4958595 0.86 SLC7A5 (0.48) SLC7A5
SCHEMBL4775852 0.86 SLC7A5 (0.48) SLC7A5
SCHEMBL8002645 0.84
SCHEMBL8712673 0.84 SLC7A5 (0.37) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
CN-115844896-A Methods of treating arenaviridae and coronaviridae virus infections 吉利德科学公司 2023-03-28 CN disclosed
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2021-02-11 US disclosed
EP-3737420-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2020-11-18 EP disclosed
US-10369091-B2 Core shell silica particles and uses thereof as an anti-bacterial agent COLGATE-PALMOLIVE COMPANY (US) 2019-08-06 US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
US-20160338920-A1 CORE SHELL SILICA PARTICLES AND USES THEREOF AS AN ANTI-BACTERIAL AGENT COLGATE PALMOLIVE CO (US) 2016-11-24 US disclosed
CN-1895066-A Anti-body leben tablet (powder) GOU CHUNHU (CN) 2007-01-17 CN disclosed
US-5747050-A COSMETICS WITH SODIUM CHLORIDE AND PEAT TORF ESTABLISHMENT (LI) 1998-05-05 US disclosed
US-5428171-A Leukotrienes antagonist; antiasthmatic, antiallergic, anti-inflammatory and cytoprotective agent MERCK FROSST CANADA, INC. (CA) 1995-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338920-A1 CORE SHELL SILICA PARTICLES AND USES THEREOF AS AN ANTI-BACTERIAL AGENT SRI, CAPG, SAE1 CHRNB2 4707/4885CHRNB4 4627/4885CHRNA3 4677/4885
US-10369091-B2 Core shell silica particles and uses thereof as an anti-bacterial agent SRI, CAPG, SAE1 CHRNB2 4707/4885CHRNB4 4627/4885CHRNA3 4677/4885
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 CHRNB2 1887/4885CHRNB4 2197/4885CHRNA3 3675/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 CHRNB2 1887/4885CHRNB4 2197/4885CHRNA3 3675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.