Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726943 | 0.83 | TTR (0.40) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL8679181 | 0.72 | TTR (0.42) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL2202782 | 0.68 | TTR (0.41) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL27368640 | 0.65 | PTPRC (0.56) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL7799561 | 0.65 | POLB (0.46) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL69805 | 0.64 | PTPRC (0.72) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL68062 | 0.64 | PTPRC (0.72) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL11937039 | 0.63 | TTR (0.52) | TTRPTPRCKMT2APOLBKDM4E | |
| SCHEMBL23651798 | 0.63 | KDM4E (0.45) | TTRPTPRCKMT2APOLBSRD5A2 | |
| SCHEMBL598301 | 0.63 | TTR (0.88) | TTRPTPRCKMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808142-A | Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |