Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940589 | 0.92 | ACE (0.59) | CCKBRACE | |
| SCHEMBL8676920 | 0.92 | ACE (0.59) | CCKBRACE | |
| SCHEMBL7486160 | 0.83 | CCKBR (0.72) | CCKBRSCN9A | |
| SCHEMBL7486156 | 0.83 | CCKBR (0.72) | CCKBRSCN9A | |
| SCHEMBL7359930 | 0.81 | ACE (0.59) | CCKBRACE | |
| SCHEMBL8283797 | 0.79 | CCKBR (0.61) | CCKBR | |
| SCHEMBL7353391 | 0.79 | ACE (0.52) | CCKBRACE | |
| SCHEMBL4797181 | 0.79 | PYGL (0.55) | CCKBR | |
| SCHEMBL4797202 | 0.79 | PYGL (0.55) | CCKBR | |
| SCHEMBL5698825 | 0.78 | CCKBR (0.60) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5532359-A | FUNGICIDES | GENENTECH, INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |