Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516193 | 0.85 | MAOB (0.58) | IDH1MEN1KMT2APKMNPC1 | |
| SCHEMBL10657318 | 0.74 | MAOB (0.52) | MEN1KMT2APKMNPC1RAB9A | |
| Valine SCHEMBL9779769 | 0.74 | SLC1A1 (0.58) | MEN1KMT2APKMALDH1A1SMN1; SMN2 | |
| Valine SCHEMBL9055966 | 0.72 | SLC1A1 (0.57) | MEN1KMT2APKMALDH1A1LTA4H | |
| Valine SCHEMBL28244846 | 0.71 | SLC15A1 (0.60) | MEN1KMT2APKML3MBTL1TDP1 | |
| Valine SCHEMBL28244847 | 0.71 | SLC15A1 (0.60) | MEN1KMT2APKML3MBTL1TDP1 | |
| SCHEMBL10659155 | 0.71 | MAOB (0.49) | MEN1KMT2APKMNPC1RAB9A | |
| Valine SCHEMBL8880104 | 0.70 | LTA4H (0.51) | MEN1KMT2AL3MBTL1MAOAMAOB | |
| SCHEMBL14032970 | 0.70 | KMT2A (0.59) | MEN1KMT2AL3MBTL1MAOBSMN1; SMN2 | |
| SCHEMBL12812710 | 0.70 | PPARG (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731344-A | DIABETES, ATHEROSCLEROSIS, ARTERIOSCLEROSIS; INHIBITORS OF ADVANCED GLYCOSYLATION ENDPRODUCTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0720608-B1 | NOVEL DIHISPIDINE DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-09 | — | — | EP | disclosed |
| WO-1995008547-A1 | NOVEL DIHISPIDINE DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-03-30 | — | — | WO | disclosed |