SCHEMBL8679404

SCHEMBL8679404

COC1(C)C[C@@H]2[C@@H](CC[C@]3(C)CCC[C@@H]23)[C@@]2(C)CCC(=O)N(C)C12

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.39
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
SRD5A1 P18405 1/20 0.35
SRD5A2 P31213 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7802581 0.76 SRD5A1 (0.58) SRD5A1SRD5A2
SCHEMBL7527164 0.76 SRD5A1 (0.58) SRD5A1SRD5A2
SCHEMBL8524586 0.68 CDK5 (0.35) CYP19A1CDK5CDK5R1SRD5A1SRD5A2
SCHEMBL4728085 0.67 CDK5 (0.34) CYP19A1CDK5CDK5R1SRD5A1
SCHEMBL8939865 0.67 SRD5A1 (0.40) SRD5A1SRD5A2
SCHEMBL8523978 0.66 HSD17B7 (0.43) CYP19A1SRD5A1SRD5A2
SCHEMBL13603645 0.66 SRD5A2 (0.47) SRD5A1SRD5A2
SCHEMBL13611189 0.66 SRD5A2 (0.47) SRD5A1SRD5A2
SCHEMBL9005677 0.66 SRD5A1 (0.56) SRD5A1SRD5A2
SCHEMBL9005680 0.66 SRD5A1 (0.56) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998009632-A1 METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR MERCK & CO., INC. (US) 1998-03-12 WO claimed