Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 9/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996740 | 0.79 | HSD17B7 (0.39) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8585120 | 0.76 | CDK5 (0.40) | CYP19A1 | |
| SCHEMBL8585118 | 0.76 | CDK5 (0.40) | CYP19A1 | |
| SCHEMBL8524586 | 0.74 | CDK5 (0.35) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996737 | 0.72 | SRD5A1 (0.38) | HSD17B7SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996741 | 0.72 | SRD5A1 (0.38) | HSD17B7SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL7527164 | 0.71 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL7802581 | 0.71 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL4728085 | 0.71 | CDK5 (0.34) | SRD5A1CYP19A1 | |
| SCHEMBL9110002 | 0.71 | HSD17B7 (0.44) | HSD17B7SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| EP-0792371-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0792371-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996012817-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | disclosed |