Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523449 | 0.81 | SRD5A1 (0.33) | SRD5A1 | |
| SCHEMBL8586469 | 0.79 | CDK5 (0.37) | CDK5CDK5R1CYP19A1STS | |
| SCHEMBL8586472 | 0.79 | CDK5 (0.37) | CDK5CDK5R1CYP19A1STS | |
| SCHEMBL8524586 | 0.77 | CDK5 (0.35) | CDK5CDK5R1CYP19A1SRD5A1 | |
| SCHEMBL8996733 | 0.72 | STS (0.30) | CYP19A1STSSRD5A1 | |
| SCHEMBL917114 | 0.72 | SRD5A1 (0.46) | SRD5A1 | |
| SCHEMBL8523662 | 0.72 | STS (0.30) | CYP19A1STSSRD5A1 | |
| SCHEMBL8996728 | 0.72 | TRPC6 (0.35) | — | |
| SCHEMBL8523925 | 0.72 | TRPC6 (0.35) | — | |
| SCHEMBL8584766 | 0.72 | MBOAT4 (0.33) | CDK5CDK5R1CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734963-A4 | METHOD OF TREATING MEN WITH METABOLIC AND ANTHROPOMETRIC DISORDERS | MERCK & CO INC (US) | 2008-06-18 | — | — | EP | claimed |
| EP-1734963-A2 | METHOD OF TREATING MEN WITH METABOLIC AND ANTHROPOMETRIC DISORDERS | Merck & Co., Inc. (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005097127-A2 | METHOD OF TREATING MEN WITH METABOLIC AND ANTHROPOMETRIC DISORDERS | MERCK & CO., INC. (US) | 2005-10-20 | — | — | WO | claimed |