SCHEMBL8679444

SCHEMBL8679444

Oc1cccc(Sc2nnn[nH]2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 6/20 0.36
HSD17B2 P37059 5/20 0.36
CA12 O43570 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CA2 P00918 2/20 0.35
CYP3A4 P08684 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
LMNA P02545 1/20 0.35
CA5A P35218 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
RET P07949 1/20 0.35
KIF5B P33176 1/20 0.35
KDR P35968 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ACHE P22303 2/20 0.32
CCNT1 O60563 1/20 0.31
CCNE2 O96020 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21552590 0.80 NOTUM (0.41) ALDH1A1SMN1; SMN2ACHE
SCHEMBL6234901 0.79 NR1H2 (0.48) CA12ALDH1A1CA2CYP3A4CA9
SCHEMBL452473 0.78 ALDH1A1 (0.35) ALDH1A1CYP3A4LMNAHSD17B10KDR
SCHEMBL9594853 0.77 TSHR (0.39) ALDH1A1HSD17B10SMN1; SMN2HDAC6TSHR
SCHEMBL3293517 0.77 ALDH1A1 (0.34) ALDH1A1CYP3A4LMNAHSD17B10SMN1; SMN2
SCHEMBL3314559 0.73 HPGD (0.35) ALDH1A1CYP3A4LMNAHSD17B10CYP2C9
SCHEMBL2239504 0.73 CA12 (0.58) HSD17B1HSD17B2CA12ALDH1A1CA2
SCHEMBL31281467 0.73 CA12 (0.58) HSD17B1HSD17B2CA12ALDH1A1CA2
SCHEMBL5199349 0.69 PNP (0.36) CA12ALDH1A1CA2CYP3A4CA14
SCHEMBL2865715 0.68 CA12 (0.50) HSD17B1HSD17B2CA12ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5187050-A Adding single replenisher containaing 3-pyrazolidone developer FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US claimed
US-5766822-A CONTAINING HYDRAZIDE COMPOUND IN HYDROPHILIC COLLOID LAYER; SENSITIVITY, CONTRAST, COPY IMAGE QUALITY FUJI PHOTO FILM CO., LTD. (JP) 1998-06-16 US disclosed
US-5356760-A Silver chlorobromide emulsion containing resorcinol-based or aminophenol-based coupler, gelatin in specifed coating weight, on support KONICA CORPORATION (JP) 1994-10-18 US disclosed
EP-0568777-A1 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1993-11-10 EP disclosed