Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003720 | 0.84 | TSHR (0.50) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL3903202 | 0.83 | AR (0.31) | — | |
| SCHEMBL10824246 | 0.80 | GABRA1 (0.37) | CYP3A4TSHRTDP1 | |
| SCHEMBL8321560 | 0.78 | P2RX7 (0.41) | — | |
| SCHEMBL631113 | 0.78 | GABRA1 (0.40) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL29403294 | 0.78 | CYP3A4 (0.41) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL477584 | 0.78 | CYP3A4 (0.41) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL4114626 | 0.74 | TSHR (0.38) | TSHRMAPK1 | |
| Water SCHEMBL28514557 | 0.74 | CYP3A4 (0.39) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL6415524 | 0.74 | TSHR (0.48) | CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876404-A | Preparation of dichlorotrifluoromethyltoluenes including novel isomers | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | claimed |
| US-4446327-A | PENTACHLORO-O-XYLENE, HYDROLYSIS, LEWIS ACID CATALYST | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | claimed |
| JP-8127553-A | — | — | None | — | — | JP | disclosed |
| JP-63270644-A | — | — | None | — | — | JP | disclosed |
| JP-63270631-A | — | — | None | — | — | JP | disclosed |
| CN-111825520-A | Preparation process of alpha, alpha' -tetrachloro-o-xylene | 西安思科赛实业有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-1998024743-A1 | TFPX SYNTHESIS | SPECIALITY COATING SYSTEMS, INC. (US) | 1998-06-11 | — | — | WO | disclosed |
| JP-H08127553-A | PRODUCTION OF FORMYL BENZOIC ACID | IHARA NIKKEI KAGAKU KOGYO KK | 1996-05-21 | — | — | JP | disclosed |
| US-4876404-A | Preparation of dichlorotrifluoromethyltoluenes including novel isomers | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4876404-A | Preparation of dichlorotrifluoromethyltoluenes including novel isomers | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
| JP-S63270631-A | NOVEL DICHLOROTRICHLOROMETHYLTOLUENE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-11-08 | — | — | JP | disclosed |
| JP-S63270644-A | NOVEL DICHLOROTRIFLUOROMETHYLNITROTOLUENE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-11-08 | — | — | JP | disclosed |
| EP-0077853-B1 | NOVEL TRIFLUOROMETHYL BENZAL CHLORIDES AND PROCESS FOR THE PREPARATION THEREOF | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-03-13 | — | — | EP | disclosed |
| US-4446327-A | PENTACHLORO-O-XYLENE, HYDROLYSIS, LEWIS ACID CATALYST | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | disclosed |
| EP-0077853-A1 | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4367348-A | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4328374-A | Process for the production of aromatic dialdehydes | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4007220-A | HYDROLYSIS | GRUPPO LEPETIT S.P.A. (IT) | 1977-02-08 | — | — | US | disclosed |