Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.52 |
| ▸ | RARA | P10276 | 14/20 | 0.52 |
| ▸ | RARG | P13631 | 13/20 | 0.52 |
| ▸ | RXRA | P19793 | 6/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356134 | 0.75 | RARG (0.64) | RARBRARARARGRXRARXRB | |
| SCHEMBL8329307 | 0.74 | RARG (0.54) | RARBRARARARGRXRARXRB | |
| SCHEMBL5846340 | 0.73 | RARB (0.77) | RARBRARARARGRXRARXRB | |
| SCHEMBL8665876 | 0.73 | RARB (0.42) | RARBRARARARGRXRA | |
| SCHEMBL9551739 | 0.72 | RARB (0.69) | RARBRARARARGRXRARXRB | |
| SCHEMBL9856398 | 0.72 | RARB (0.62) | RARBRARARARGRXRARXRB | |
| SCHEMBL3590710 | 0.70 | RARB (0.54) | RARBRARARARGRXRARXRB | |
| SCHEMBL7156350 | 0.70 | RARB (0.50) | RARBRARARARGRXRARXRB | |
| SCHEMBL8679599 | 0.69 | RARA (0.55) | RARBRARARARGRXRARXRB | |
| SCHEMBL10549628 | 0.69 | RARG (0.57) | RARBRARARARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728739-A | LIGANDS WITH AFFINITY FOR RETINOIC ACID RECEPTORS IN SYNERGISTIC COMBINATION WITH A FATTY ACID, TREATMENT OF DIABETES, CARDIOVASCULAR DISEASE, ATHEROSCLEROSIS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-03-17 | — | — | US | disclosed |