Terephthalamide

Terephthalamide

SCHEMBL8679694

C1CCCNCC1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.47
PARP10 Q53GL7 8/20 0.46
PARP15 Q460N3 3/20 0.46
PARP4 Q9UKK3 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 1/20 0.46
PARP14 Q460N5 1/20 0.46
PARP16 Q8N5Y8 1/20 0.46
PARP11 Q9NR21 1/20 0.46
PARP1 P09874 2/20 0.46
TSHR P16473 2/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL27861496 1.00 OPRD1 (0.47) OPRD1PARP10PARP15PARP4ALDH1A1
Terephthalamide SCHEMBL10631357 0.98 OPRD1 (0.46) OPRD1PARP10PARP15PARP4ALDH1A1
Piperidine SCHEMBL27584865 0.90 KMT2A (0.49) OPRD1PARP10PARP15PARP4ALDH1A1
Benzamide SCHEMBL694831 0.90 TSHR (0.64) OPRD1PARP10PARP15ALDH1A1KMT2A
Benzamide SCHEMBL4726018 0.87 TSHR (0.67) OPRD1PARP10ALDH1A1KMT2APARP1
Piperidine SCHEMBL28849723 0.86 PARP10 (0.70) PARP10PARP15PARP4ALDH1A1KMT2A
Terephthalamide SCHEMBL12613686 0.85 PARP1 (0.60) PARP10PARP15PARP4ALDH1A1KMT2A
Terephthalamide SCHEMBL472214 0.85 PARP1 (0.60) PARP10PARP15PARP4ALDH1A1KMT2A
Terephthalamide SCHEMBL197479 0.85 PARP1 (0.60) PARP10PARP15PARP4ALDH1A1KMT2A
Terephthalamide SCHEMBL4131585 0.83 PARP1 (0.57) PARP10PARP15PARP4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5798403-A BLEND OF KAOLIN, POLYAMIDE, COPOLYMER CONTAINING UNSATURATED ACID, AROMATIC VINYL COMPOUND AND VINYL CYANIDE AND GRAFT POLYMER CONTAINING VINYL COMPOUND AND DIENE RUBBER KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-08-25 US disclosed