Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676570 | 0.92 | SENP7 (0.42) | MAPTRAB9AL3MBTL1LMNANPC1 | |
| SCHEMBL8679540 | 0.92 | PTGER1 (0.44) | MAPTRAB9ANPC1SENP7KMT2A | |
| SCHEMBL8677143 | 0.90 | HPGD (0.40) | MAPTRAB9AL3MBTL1LMNANPC1 | |
| SCHEMBL8678027 | 0.90 | NPC1 (0.46) | MAPTRAB9AL3MBTL1NPC1CASP3 | |
| SCHEMBL8676393 | 0.86 | MRGPRX4 (0.47) | SMN1; SMN2FFAR4MRGPRX4HDAC1 | |
| SCHEMBL8675846 | 0.85 | SLC22A12 (0.40) | MAPTRAB9AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8679823 | 0.83 | PPARA (0.40) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8678035 | 0.83 | PPARG (0.41) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8678804 | 0.82 | PDE4A (0.42) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8677002 | 0.81 | PDE4A (0.41) | RAB9ANPC1KMT2APPARGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |