Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679799 | 0.92 | MAPT (0.42) | HDAC6HDAC8HDAC1MRGPRX4HPGD | |
| SCHEMBL8678027 | 0.90 | NPC1 (0.46) | HDAC6MRGPRX4HPGDNPC1RAB9A | |
| SCHEMBL8676570 | 0.90 | SENP7 (0.42) | HDAC1MRGPRX4NPC1RAB9AATM | |
| SCHEMBL8677143 | 0.88 | HPGD (0.40) | HDAC6HDAC8HDAC1MRGPRX4HPGD | |
| SCHEMBL8679538 | 0.85 | L3MBTL1 (0.42) | PPARAHDAC6HDAC8HDAC1MRGPRX4 | |
| SCHEMBL8676393 | 0.84 | MRGPRX4 (0.47) | HDAC1MRGPRX4 | |
| SCHEMBL8675846 | 0.83 | SLC22A12 (0.40) | MRGPRX4HPGDRAB9AMEN1KMT2A | |
| SCHEMBL8679823 | 0.82 | PPARA (0.40) | PPARANPC1RAB9AMEN1KMT2A | |
| SCHEMBL8678035 | 0.81 | PPARG (0.41) | HDAC8NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8678804 | 0.80 | PDE4A (0.42) | HDAC1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |