Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607518 | 0.80 | LMNA (0.48) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL2646503 | 0.79 | MEN1 (0.38) | ALDH1A1MAPTMAPK1LMNAKDM4E | |
| SCHEMBL4620598 | 0.78 | HCAR2 (0.37) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL28347013 | 0.77 | LMNA (0.46) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL7950766 | 0.74 | KDM4E (0.46) | ALDH1A1MAPTMAPK1LMNAKDM4E | |
| SCHEMBL8680389 | 0.74 | HCAR2 (0.34) | ALDH1A1MAPTMAPK1KDM4ETSHR | |
| SCHEMBL734433 | 0.73 | HCAR2 (0.35) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL20263547 | 0.71 | KDM4E (0.49) | ALDH1A1MAPTMAPK1LMNAKDM4E | |
| SCHEMBL4449462 | 0.70 | TSHR (0.49) | ALDH1A1MAPK1LMNATSHRHSD17B10 | |
| SCHEMBL24373045 | 0.70 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255305-B1 | PSYCHOLOGICAL DISORDERS | MERCK SHARP & DOHME LIMITED (GB) | 2001-07-03 | — | — | US | disclosed |