Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683912 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL8679659 | 0.99 | PTGS1 (0.56) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL8680165 | 0.94 | MAPT (0.57) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL8679637 | 0.89 | MAPT (0.60) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| Benzoic Acid SCHEMBL11497214 | 0.88 | LTB4R (0.47) | ALDH1A1 | |
| SCHEMBL8679374 | 0.84 | ALDH1A1 (0.66) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL2552649 | 0.84 | TBXAS1 (0.54) | MAPTALDH1A1LMNACNR2 | |
| SCHEMBL2550963 | 0.84 | TBXAS1 (0.54) | MAPTALDH1A1LMNACNR2 | |
| SCHEMBL1290373 | 0.84 | TBXAS1 (0.54) | MAPTALDH1A1LMNACNR2 | |
| SCHEMBL2555641 | 0.84 | TBXAS1 (0.54) | MAPTALDH1A1LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037052-A1 | PREPARATION OF ARYL BROMOARYL KETONES AND CARBOXYLIC DERIVATIVES THEREOF | ALBEMARLE CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |