Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595400 | 0.76 | CYP2D6 (0.38) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL29843526 | 0.74 | S100A4 (0.39) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL10344203 | 0.69 | MEN1 (0.55) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL30665368 | 0.69 | MEN1 (0.55) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL2405982 | 0.67 | MAPT (0.44) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL30895284 | 0.66 | MAOA (0.50) | ALOX15CA12CA9KMT2ACA1 | |
| SCHEMBL503745 | 0.66 | MAOA (0.50) | ALOX15CA12CA9KMT2ACA1 | |
| SCHEMBL7354968 | 0.66 | MAOA (0.50) | MAPTHTTALOX15CA12CA9 | |
| Hydrochloric Acid SCHEMBL26614007 | 0.65 | MAOA (0.48) | ALOX15CA12CA9KMT2ACA1 | |
| SCHEMBL5982033 | 0.64 | KDM4E (0.44) | MAPTPTGS1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808142-A | Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |