SCHEMBL8680649

SCHEMBL8680649

C=C(C)c1cccc(CC(C)Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.40
PNMT P11086 1/20 0.40
FOLH1 Q04609 4/20 0.36
ANPEP P15144 1/20 0.36
ENPEP Q07075 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9814342 0.84 SLC7A5 (0.41) SLC7A5PNMTFOLH1ANPEPENPEP
SCHEMBL28097746 0.84 PNMT (0.53) SLC7A5PNMTANPEPENPEPTAAR1
SCHEMBL8377661 0.80 SLC7A5 (0.38) SLC7A5PNMTFOLH1ANPEPENPEP
SCHEMBL45023 0.79 PNMT (0.52) PNMTTAAR1
SCHEMBL15896437 0.79 SLC7A5 (0.50) SLC7A5FOLH1ANPEPENPEP
SCHEMBL11600508 0.78 TSHR (0.39) FOLH1
SCHEMBL8677286 0.78 TAAR1 (0.35) TAAR1
SCHEMBL7762101 0.78 FOLH1 (0.45) SLC7A5FOLH1ANPEPENPEP
SCHEMBL608583 0.76 LOXL2 (0.37) FOLH1
SCHEMBL1363307 0.76 BCL2 (0.43) SLC7A5FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719096-A ISOMER BLEND; CROSSLINKING POLYMERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-02-17 US disclosed
US-5539061-A FOR CROSSLINKING THERMOPLASTIC RESINS, POLYETHYLENE, ETHYLENE-PROPYLENE COPOLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-23 US disclosed